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Chromogenic Kits

Learn more about our Chromogenic Kits.

Phospholipid Emulsions

Our highly stable phospholipid emulsions are suitable for use in analyses related to procoagulant and anticoagulant pathways.

References

Rox FIX-A

Ref: 950030

A chromogenic kit for quantitative determination of preactivatede Factor IX (FIXa) in human Factor IX concentrates.

The kit method comprises activation of human FX by sample FIXa in the presence of FVIII, thrombin, calcium ions and phospholipids. Generated FXa is directly proportional to the FIXa activity in the sample and is measured through hydrolysis of a chromogenic FXa substrate.

- A chromogenic kit based upon FXa generation.

- Quantification limit = 0.02 mIU/ml FIXa.

- Detects a preactivation level in the order of 0.002%.

- 1 Kit = 2 x 50 tests.

- Reconstituted reagents are stable for 72 h at 2-8°C.

- Factor IXa Calibrator and Control available.

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News

2019-06-20 ISTH, Melbourne July 6-10, 2019.

Rossix will present three posters related to analysis of Factor IX at the ISTH in Melbourne:

PB0099 - Evaluation of Lupus Anticoagulant interference in a chromogenic Factor IX kit for determination of

Factor IX activity

PB1294 - Assessment of Factor IX Padua activity with a one-stage clotting method and with FXIa- and tissue factor/FVIIa-based chromogenic methods

PB1295 - Recombinant Factor IX fused with albumin (rFIX-HSA) is underassigned by one-stage methods with silica as contact activator

More information

  

2016-06-22 Publication in collaboration with NovoNordisk

Rosén P, Rosén S, Ezban M, Persson E.

Overestimation of N-glycoPEGylated factor IX activity in one-stage factor IX clotting assay owing to silica-mediated premature conversion to activated factor IX.

J Thromb Haemost 2016; 14: 1420-7.

  

2015-04-13 Publication in collaboration with AstraZeneca

Ann Lövgren et al. Blood Coagulation and Fibrinolysis, Characterization of thrombin derived from 

human recombinant prothrombin.

Open access: click here

  

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