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Chromogenic Kits

Learn more about our Chromogenic Kits.

Phospholipid Emulsions

Our highly stable phospholipid emulsions are suitable for use in analyses related to procoagulant and anticoagulant pathways.

References

BSA

All new batches of Bovine Serum Albumin (BSA) are carefully validated prior to approval for use in Rossix buffers and reagents.

Approval of a new batch of BSA consists of the following:

Test as bulking agent - FVIII method

The BSA is tested as a bulking agent in a FVIII method. The stability and performance of sample and reagent solutions is evaluated.

Test as bulking agent - FVII method

The BSA is tested as a bulking agent in a FVII method. The stability and performance of sample and reagent solutions is evaluated.

 

Absence of proteas activity

The new batch is tested for absence of proteas activity by incubation with a chromogenic substrate with a broad selectivity.

Control of origin

Rossix requests documents which demonstrates the source of bovine plasma used for manufacturing of BSA to originate from countries shown to be free from TSEs affecting animals, including BSE and scrapie.

News

2018-06-29 Posters at the SSC meeting in Dublin July 18-21, 2018.

Steffen Rosén and Rossix AB will present two posters at the SSC meeting in Dublin:

PB229 - Overestimation of recombinant wild type FIX potency by a one-stage method indicated from comparison with a chromogenic FXIa and TF/FVIIa based methods and through discrepant activation of rwtFIX and plasma derived FIX by plasma kallikrein.

PB238 - Underassignment of FIX potency of rFIX-Albumin fusion protein by one-stage methods demonstrated in studies on FXIa and FIXa generation. 

  

2016-06-22 Publication in collaboration with NovoNordisk

Rosén P, Rosén S, Ezban M, Persson E.

Overestimation of N-glycoPEGylated factor IX activity in one-stage factor IX clotting assay owing to silica-mediated premature conversion to activated factor IX.

J Thromb Haemost 2016; 14: 1420-7.

  

2015-04-13 Publication in collaboration with AstraZeneca

Ann Lövgren et al. Blood Coagulation and Fibrinolysis, Characterization of thrombin derived from 

human recombinant prothrombin.

Open access: click here

  

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